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Plenary Sessions



                P4.1      Living with the Chronic – What Could be Done at Primary    16:15 Convention Hall B
                          Care

               The Challenge of Managing Multiple Chronic Conditions
               Guthrie B
               Population Health Sciences Division, University of Dundee, UK                                       HOSPITAL AUTHORITY CONVENTION 2018

               The challenges faced by health services continually evolve. In the first epidemiological transition, patterns of disease shifted
               from being dominated by acute conditions and trauma to non-communicable diseases or long-term conditions. Common
               responses by healthcare systems include the widespread dissemination of clinical guidelines and the development of
               structured care pathways with disease registers supporting regular recall to structured care. However, we are now in the
               midst of a second epidemiological transition with increasing number of people now living with multiple long-term conditions.
               It is important to recognise that multimorbidity is in part the price of success. Better survival from acute conditions like stroke,
               cancer, premature birth and trauma is a triumph, but it means that more people survive with long-term conditions. Increased
               life expectancy is to be celebrated, but in turn contributes to rapid population ageing. However, despite the increase in
               multimorbidity, healthcare systems remain built around specialist care organised by body systems most commonly located in
               hospitals. Virtually all clinical guidelines are for specific conditions, and are based on evidence from clinical trials that exclude
               the majority of people with the condition the guideline is for. Clinical professionals, patients and families often struggle with
               optimising the risks and benefits of treatment in complex patients, and in providing effective treatment to those that can
               benefit while avoiding futile or harmful treatment in those that cannot. There is no simple solution to the challenges posed by
               multimorbidity. This presentation will describe the epidemiology of multimorbidity, the challenges multimorbidity poses for
               clinicians, policymakers and guideline developers, and ways in which health services and individual clinicians can respond to
               optimise care.                                                                                      Monday, 7 May 2018















                P4.2      Living with the Chronic – What Could be Done at Primary    16:15 Convention Hall B
                          Care

               How Can We Respond to the Global Challenge of Dementia?
               Wittenberg R
               London School of Economics and Political Science, UK
               Dementia has huge impacts on the quality of life of people living with the condition and their carers and huge impacts on
               society more generally. Around 50 million people worldwide are living with dementia. Rising numbers of older people mean
               that worldwide the number living with dementia could treble by 2050.
               There are three major challenges to address in responding to this global challenge: prevention, treatment and care. One third
               of cases of dementia are potentially preventable. Key risks factors include: in early life, level of education; in mid-life, hearing
               loss, hypertension and obesity; and in later life, smoking, depression, physical inactivity, social isolation and diabetes. How
               can we best reduce these risks?

               There is currently no cure for dementia. All trials of potential disease-modifying drugs in recent years have failed and some
               pharmaceutical companies have ceased research and development in this field. Others are currently conducting trials of such
               drugs. A new drug which delayed onset of Alzheimer’s disease by three years could reduce societal costs of care by 30%
               (before allowing for the costs of the drug). How should healthcare systems best prepare for the potential availability of new
               drugs which prove effective but possibly costly?

               People living with dementia require timely diagnosis, high  quality  long-term  care and  support and ultimately end-of-life
               care. Most of this care in high-, middle- and low-income countries is provided by unpaid carers. They too may require care
               and support. There are some symptomatic drugs which have been found to be cost-effective. Some non-pharmaceutical
               treatments, including cognitive stimulation therapy, have also proved cost-effective in improving quality of life for people with
               dementia and carers. How can these interventions be effectively made available to a higher proportion of people living with
               dementia?
               Tackling these challenges needs international cooperation to promote research and development and to facilitate learning
               between countries. To this end, World Health Organization has recently established a Global Dementia Observatory and a
               global action plan on the public health response to dementia.



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