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Service Enhancement Presentations



                F8.6      Young HA Investigators Presentations                             14:30  Room 421

               The Impact of Structured Pharmacist Counseling on Adherence and Knowledge of Patients on Oral
               Chemotherapy
               Lam HK, So KH, Chan MC, Lee SC                                                                      HOSPITAL AUTHORITY CONVENTION 2017
               Department of Pharmacy, Prince of Wales Hospital, Hong Kong

               Introduction
               Overseas studies had revealed the issue of non-adherence among patients on oral chemotherapy which could lead to life-
               threatening outcome. These studies further indicated the positive impact of structured and regular pharmacist counseling
               service on patient’s adherence to oral chemotherapies.

               Objectives
               To evaluate the impact of structured pharmacist counseling on adherence, knowledge and pharmaceutical care of patients
               newly initiated with oral chemotherapy.
               Methodology
               This study is a prospective, single-centre randomised control trial. Subjects in the intervention group received structured
               counseling sessions provided by pharmacist before each treatment cycle. The control group received standard single
               pharmacist counselling session before the first treatment cycle. A modified version of Morisky Medication Adherence
               Scales – 4 (MMAS-4) was used to evaluate the adherence of subjects to their oral chemotherapy. Any positive answer to
               the four questions in modified MMAS-4 was considered as non-adherence. Furthermore, phone number for emergency in
               pharmacist consultation service was offered to all subjects if needed.
               Results
               98 patients were included in the study. Three months after the initiation of oral chemotherapy, the non-adherence rate of
               intervention group and control group were found to be 8.2% and 38.8% respectively (p=0.018). A total of 68 calls were
               received via the phone number for emergency in pharmacist consultation service and 31.0% of subjects were referred to
               doctors for further management. The total number of visits to Accident and Emergency Department was 16 in the control
               group and eight in the intervention group (p=0.015). Regarding patient’s knowledge on drug treatment, the percentage of
               subjects possessing knowledge on vomited dose management (intervention group 71.4% vs control group 6.1%, p<0.0001)
               and missed dose management (intervention group 59.2% vs control group 18.4%, p<0.0001) was found to be significantly
               improved with the intervention.                                                                     Wednesday, 17 May












































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