Kidney Transplant Kidney Transplant Center

About Kidney Transplant Center


Queen Mary Hospital is the first kidney transplant center in Hong Kong. Our first kidney transplant was performed in 1969. Apart from deceased donor kidney transplant, we also started live donor kidney transplantation services since 1983. Queen Mary Hospital is the only hospital providing multi-organ transplant service in Hong Kong. Our first combined kidney and liver transplantation was performed in 1994. In 2017, we performed the first ABO incompatible kidney transplant in Hong Kong.

Our kidney transplantation team has played leading role in the diagnosis and management of post-transplant infections. In the 80’s, we were the first centre that established anti-HCV assay (Nephrology in collaboration with Hepatology service) for the management of Hepatitis C infection in patients with kidney disease in Hong Kong. In the 90’s, we first established in Hong Kong the HBVDNA assay ( Nephrology service) for diagnosis and management of Hepatitis B infection in kidney transplant recipients. We have also first established the CMVpp65 antigenaemia assay (Nephrology in collaboration with Microbiology service) for diagnosis and management of Cytomegalovirus infection in transplant patients.

The Combined Renal Replacement Services of Queen Mary Hospital provides comprehensive care to patients with end stage kidney failure who need renal replacement therapy. Our multi-disciplinary team consisting of nephrologists, urologists, nurses, other professional and allied health staff that provide professional services to kidney transplant recipients and live kidney donors. These services include pre-transplantation assessment and long term management for kidney transplant recipients, and pre-donation suitability assessment and post-donation long term care for live kidney donor.

At the end of June 2017, our hospital has already performed over 600 kidney transplantation surgery and over 1000 patients have been under the care of our transplant team. We also actively engage in researches in the field of transplantation medicine to solicit ways to improve our care, reduce complications and enhance patient survival.

Milestones

Milestones of
Kidney Transplant Center


The first deceased donor kidney transplantation in Hong Kong took place in Queen Mary Hospital in 1969. We performed our first live donor kidney transplant in 1983. Our first combined kidney and liver transplantation was performed in 1994. In 2017, we performed the first ABO incompatible kidney transplant in Hong Kong.


NOW

1st ABO incompatible kidney transplantation

2017

500th kidney transplantation

2011

1st laparoscopic donor nephrectomy for live donor

2001

1st combined kidney liver transplant

1994

1st paediatrics kidney transplantation

1990

1st live donor (unrelated) kidney transplant

1988

100th kidney transplantation

1987

1st live donor (related) kidney transplantation

1983

1st deceased donor kidney transplant

1969

Transplant Recipient's Survival Rates

As of 30 June 2024, a total of 762 kidney transplants have been performed, in which 260 were live donor kidney transplantation and 502 were deceased donor kidney transplantation.

Between 1996 and June 2017, the overall 1-year, 3-year and 5-year patient survival rates were 97%, 93% and 91% respectively. For live donor kidney transplant, the patient survival rates were 98%, 98% and 98 % respectively. For deceased donor kidney transplant, the rates were 96%, 91% and 87% respectively.



Overall Recipient Survival Rates
Overall Recipient Survival Rates





1 Year

97%





3 Years

93%





5 Years

91%

Our Multi-disciplinary Team

Nephrologist

Prof. CHAN Daniel Tak Mao
(Division Chief)

Dr. CHOY Bo Ying Cindy
(Director of Combined Renal Replacement Services(Medical))

Prof. TANG Sydney Chi Wai
Dr. WANG Yee Moon Angela
Dr. YAP Desmond Yat Hin
Dr. MA Kam Man Maggie
Dr. CHAN Chi Wang Gary
Dr. KWAN Pui Yuen Lorraine
Dr. LUI Sing Leung
Dr. YIP Pok Siu Terence
Dr. MOK Ming Yee Maggie



Urologist

Dr. TSU Hok Leung James
(Division Chief & Director of Combined Renal Replacement Services (Surgical))

Dr. MA Wai Kit
Dr. NG Tsui Lin Ada
Dr. HO Sze Ho Brian
Dr. LAM Pei Wayne
Dr. TSANG Chiu Fung
Dr. LAI Chun Ting Terence



Renal Nurse and Supporting Team



Education Corner

Kidney Transplant Information

Kidney transplant is the preferred treatment modality for most end stage renal failure (ESRF) patients. A kidney from a healthy person (usually a close relative) or a deceased cadaveric donor is transplanted to the patient under general anaesthesia. Prior to transplantation, the patient and the donor shall go through all the blood and urine tests and medical examinations. If transplantation is successful, the patient will no longer need to undergo dialysis treatment but must take life-long immunosuppressants to keep the body from rejecting the kidney.


Risks and Complications

  • Surgical complications include: Wound infection, Bleeding, Leakage of urine, Renal artery or vein thrombosis, Stenosis of renal artery, Stenosis of ureter, Lymphocele
  • Dysfunctioning of transplanted kidney due to rejection, commonly classified as hyperacute, acute or chronic.
  • It is possible that transplantation may introduce infection or other donor-derived disease to the recipient
  • Recurrence of particular type of glomerulonephritis may adversely affect the function of transplanted kidney.
  • Immunosuppressants may increase the chance of developing certain forms of malignant tumors, lymphoproliferative tumors and lymphoproliferative disease (e.g. lymphoma) and infection.




Post-Transplant Drug Information

It is important for patients to be compliant to the prescribed immunosuppressant in order to prevent rejection and maintain stable graft kidney function. Our doctors will monitor the drug level and review immunosuppressant regime regularly.

The commonly used immunosuppressants (anti-rejection medicine) are:
1. Prednisolone
2. Cyclosporin A
3. Tacrolimus
4. Mycophenolate Mofetil / Mycophenolate sodium
5. Azathioprine
6. m-TOR inhibitor(Sirolimus/Everolimus)





Post Kidney Transplant Patient Care

  • To monitor the progress of transplantation, the patient will have to undergo blood and other tests (e.g. imaging and graft biopsy)
  • To achieve optimal results, the patient must follow the dietitian’s advice on diet restrictions and maintain optional optimal body weight.
  • The patient must take anti-rejection medicine every day and attend follow-up to adjust dosage of medication.
  • To avoid having side effects, when the patient seeks medical consultation from another doctor, he/she must show all the drugs including immunosuppressants to the doctor to avoid drug interaction.
  • The patient must inform the renal centre of the following: Fever, chills; General discomfort; Swelling of the eyes or legs etc.; Decreased urine output; Sudden weight gain; Feeling of swelling or pain over the wound; High blood pressure; Burning sensation during urination; Passing blood in urine
  • There may be other abnormalities caused by infection. Should the patient feels unwell he/she must inform the health care professionals immediately or seek emergency treatment from hospital.




Kidney Donor Information

It is respectable to donate one of your kidneys to save your beloved. The relationship between the donor and recipient becomes even more intimate due to this act of love. Kidney donation should be based on love and care, but not on any social pressure or financial reward.

If you want to donate kidney to your beloved, please express your donation wish to our medical staff. Our kidney transplant team will arrange counseling and assessment for you before deciding whether you are suitable kidney donor.

For further information on kidney donation and transplantation, please contact our medical staff or visit the related websites.

Patient Support Group

Renal Companion Association

Renal Companion Association was established by a group of kidney transplant recipients in 1987 and is dedicated to improve the care and quality of life of kidney patients through education, advocacy and developing patient communities.

Contact
Telephone: 2794 3010
Fax: 2338 4820
Mail: PO BOX 20260, Hennessy Road Post Office, HK

Membership Application Form

腎臟移植中心

關於腎臟移植中心


瑪麗醫院為全港首個腎臟移植中心。全港首宗腎臟移植於1969年在本院進行。除了遺體腎移植,本院亦於1983年開始了活體腎臟移植服務。瑪麗醫院為全港唯一多器官移植中心。全港首宗肝腎移植於1994年於本院進行。此外,本院亦於2017年進行了本地首宗血型不相容腎臟移植。
我們一向致力改善對移植病人感染的治理。從八十年代開始,腎科與肝臟科合作創立了本港首個丙型肝炎病毒抗體檢測。其後於九十年代,腎科創立了本港首個乙型肝炎病毒DNA測試,為受感染乙型肝炎的移植病人作出檢測及治理。腎科亦與微生物科合作,創立本港首個巨細胞病毒(CMV) pp65抗原血癥檢測,為感染巨細胞病毒的移植病人作出檢測及治理。
我們的跨專科腎移植團隊包括腎科專科醫生,泌尿科專科醫生,護理以及其他專科和專職醫療人員。我們的腎臟移植專科服務包括為腎衰竭病人進行腎臟移植評估及術後治療,以及為活體腎捐贈者作捐贈手術前的身體評估和捐贈後的長期監察治療。
直至二零一七年六月底,瑪麗醫院已進行了超過600個腎臟移植手術,亦為1000多名腎移植病人提供覆診治療。除了臨床服務外,我們亦致力推動移植醫學的科學研究與教育,並應用科研成果於日常服務,以提升病人存活率及減少併發症。

服務里程碑

腎臟移植中心里程碑


全港首個腎臟移植於1969年在瑪麗醫院進行。 本院於1983年進行了首個活體腎臟移植。 全港首宗肝腎移植亦於1994年於本院進行。 此外,本院於2017年進行了本港首宗血型不相容腎臟移植。


現時

首例血型不相容腎臟移植

2017

第500宗腎臓移植

2011

首例腹腔鏡活體腎臓捐贈手術

2001

首例肝腎移植

1994

首例小兒活體腎臓移植

1990

首例活體腎臓移植(非血縁親屬)

1988

第100宗腎臓移植

1987

首例活體腎臓移植(血縁親屬)

1983

首例人體腎臓移植

1969



腎臓移植病人存活率

截至二零二四年六月三十日, 瑪麗醫院總共完成762宗腎臓移植。 當中 260宗是活體腎臓移植、 502宗是遺體腎臓移植。

在1996至2017年6月期間,整體一年、三年、和五年的病人存活率分別是97%,93% 和91%。 活體腎臓移植的病人存活率分別是98%,98%和98%。 而遺體腎臓移植則分別是96%,91%和87%。



腎臓移植病人存活率
腎臓移植病人存活率





一年

97%





三年

93%





五年

91%

我們的跨專科腎移植團隊

腎科專科醫生

陳德茂講座教授 (腎科主管)
蔡寶英醫生 (綜合腎科透析及移植服務總監(內科))
鄧智偉講座教授
王依滿醫生
葉逸軒醫生
馬錦文醫生
陳志弘醫生
關佩玄醫生
雷聲亮醫生
葉樸韶醫生
莫明兒醫生

泌尿科專科醫生

徐學良醫生 (泌尿科主管及綜合腎科透析及移植服務總監(外科))
馬偉傑醫生
吳翠蓮醫生
何思灝醫生
林沛弘醫生
曾昭鋒醫生
賴俊廷醫生



腎科護士及支援團隊



腎臓移植資訊

腎臟移植,俗稱「換腎」,為大部份末期腎衰竭病者最理想的治療方式。病者需要接受全身麻醉手術,接受將一個由健康的人(通常是近親)或剛去逝病人所捐贈的健康腎臟移植到病者體內。在腎臟移植前,病者及近親都需作血液、尿液測試及身體檢查。 成功移植後的病者,不需再接受透析治療,但必須長期服用免疫抑制藥物,以防止排斥發生。


手術風險或併發症

  • 與手術有關之併發症: 傷口發炎; 傷口流血; 傷口漏尿; 移植腎動脈或靜脈血栓形成; 移植腎動脈血管收窄; 移植輸尿管收窄; 淋巴囊腫。
  • 對「移植腎」產生排斥而引至腎功能衰退。排斥包括「高度急性排斥」,「急性排斥」及「慢性排斥」。
  • 有機會經移植腎而感染到其它傳染病及其它疾病。
  • 個別腎小球性腎炎復發而影響移植腎的功能。
  • 由抗排斥藥誘發之惡性腫瘤或淋巴組織增生的疾病,如淋巴瘤等。

移植後藥物簡介

跟隨醫生指示服藥是預防排斥及維持移植腎功能穩定的最重要一環。我們的醫生團隊會定時監察藥物血濃度及調整抗排斥藥藥量。

下列是常用的抗排斥藥:
1.腎上腺激素(Prednisolone),俗稱「肥仔藥」
2. 環孢素(Cyclosporin A)
3. 普樂克復(Tacrolimus)
4. 驍悉/米芙(Mycophenolate Mofetil/ Mycophenolate sodium)
5. 硫唑嘌呤(Azathioprine)
6. 雷帕鳴/依維莫司(Rapamycin/ Everolimus)










腎臓移植術後的護理

  • 為了更能掌握病情,病者須接受血液及其它有關檢查,如造影、穿刺等
  • 為使腎臟移植治療達到理想效果,病者必須按營養師指導飲食,嚴格遵守飲食限制及維持適當體重
  • 病者須定時服用指定藥物,以防止排斥現象發生。並定時覆診,調較葯物劑量。
  • 當向其他醫生求診時,要出示所服的排斥藥物,避免服用其他藥物後產生不良作用
  • 如遇以下情況,必須向腎科中心報告: 發熱、發冷; 全身不適; 水腫,如眼腫,腳腫; 小便減少; 體重突然增加; 手術部位疼痛及脹硬的感覺; 血壓高; 小便刺痛; 血尿。
  • 其他身體不尋常現象亦可能由於受感染而產生。若有身體不適應盡快通知醫護人員或到就近急症室診治,避免延誤醫治


活體腎捐贈者資訊

捐贈自己的一個腎臟,以解救至愛親友的病痛,實為一偉大行為。捐贈者與接受者深切感受對方的關懷,相互關係更益密切。 唯此決定必須基於愛護,出自摯誠,不受任何社會壓力所影響,也不應從中獲取金錢或物質的回報。

如果閣下有意捐贈腎臟予親人,請約見我們醫護人員。腎臓移植組會為閣下進行一系列的健康狀況評估,也會轉介閣下到心理專家進行心理評估及輔導,以決定閣下是否適合捐出腎臟。

若想知道更多有關腎臟捐贈及移植的資科,可聯絡我們的醫護人員或瀏覽相關的網址。

病人互助組織

病人互助組織


腎之友

腎之友於一九八七年由一群已接受腎臟移植的腎病康復者所組成的自助組織,並向政府社團註册處註册, 及獲香港稅務局豁免稅收,成為註册非牟利團體。

聯絡方法
電話: 2794 3010
傳真: 2338 4820
地址: 香港灣仔軒尼詩道郵政局郵箱20260號

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